Local corticosteroids in asthma.

Inhaled corticosteroids in asthma management.

Asthma is a disorder of the lower airways, characterized by bronchial hyperresponsiveness and airflow limitation, the pathogenesis of which is yet to be fully understood. Regardless of its triggers, asthma's hallmark is a state of inflammation that, when uncontrolled, results in persistence of symptoms. Inhaled corticosteroids are established as the mainstay of asthma therapy. This paper examin...

Corticosteroids in the treatment of acute asthma

Asthma is a prevalent chronic disease of the respiratory system and acute asthma exacerbations are among the most common causes of presentation to the emergency department (ED) and admission to hospital particularly in children. Bronchial airways inflammation is the most prominent pathological feature of asthma. Inhaled corticosteroids (ICS), through their anti-inflammatory effects have been th...

Corticosteroids in treatment of chronic asthma.

Chronic or continuous bronchial asthma is a disabling and potentially dangerous disorder, for which the only effective treatment in the majority of cases is the administration of corticosteroids. There was at first some reluctance to use these agents on a long-term basis, mainly because of a discouraging report from the Medical Research Council (1956), but in the past nine years many well-docum...

How do corticosteroids work in asthma?

Corticosteroids (or glucocorticosteroids) are widely used to treat various inflammatory and immune diseases. The most common use of corticosteroids today is in the treatment of asthma, and inhaled corticosteroids have become established as first-line treatment in adults and children with persistent asthma, the most common chronic inflammatory disease. Recent developments in understanding the fu...

Effects of corticosteroids in acute severe asthma.